Hydromorphone
COMMON & BRAND NAMES
Dilaudid, Hydrostat, Palladone
EFFECTS CLASSIFICATION
Analgesic, Antitussive
CHEMICAL NAME
4,5-epoxy-3-hydroxy-17-methylmorphinan-6-one
DESCRIPTION
Hydromorphone is an opiate, narcotic analgesic, used primarily in the treatment of moderate to severe pain. It is a semi-synthetic derivative of morphine.
EFFECTS
The major hazards of DILAUDID ORAL LIQUID and DILAUDID 8 mg TABLETS include respiratory depression and apnea. To a lesser degree, circulatory depression, respiratory arrest, shock and cardiac arrest have occurred. The most frequently observed adverse effects are light-headedness, dizziness, sedation, nausea, vomiting, sweating, flushing, dysphoria, euphoria, dry mouth, and pruritus. These effects seem to be more prominent in ambulatory patients and in those not experiencing severe pain.
Less Frequently Observed Adverse Reactions:
General and CNS: Weakness, headache, agitation, tremor, uncoordinated muscle movements, alterations of mood (nervousness, apprehension, depression, floating feelings, dreams), muscle rigidity, paresthesia, muscle tremor, blurred vision, nystagmus, diplopia and miosis, transient hallucinations and disorientation, visual disturbances, insomnia, increased intracranial pressure
Cardiovascular: Flushing of the face, chills, tachycardia, bradycardia, palpitation, faintness, syncope, hypotension, hypertension.
Respiratory: Bronchospasm and laryngospasm
Gastrointestinal: Constipation, biliary tract spasm, ileus, anorexia, diarrhea, cramps, taste alteration
Genitourinary: Urinary retention or hesitancy, antidiuretic effects
Dermatologic: Urticaria, other skin rashes, diaphoresis.
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